Publications

1. UHRF1 is essential for proper cytoplasmic architecture and function of mouse oocytes and derived embryos.

Uemura S, Maenohara S, Inoue K, Ogonuki N, Matoba S, Ogura A, Kurumizaka M, Yamagata K, Sharif J, Koseki H, Ueda K, Unoki M, Sasaki H

Life Sci Alliance (2023);6

 

2. Extracellular vesicles secreted from bone metastatic renal cell carcinoma promote angiogenesis and endothelial gap formation in bone marrow in a time-dependent manner in a preclinical mouse model.

Takeda M, Sakamoto H, Shibasaki N, Fukui T, Magaribuchi T, Sumiyoshi T, Utsunomiya N, Sawada A, Goto T, Kobayashi T, Ueda K, Yamasaki T, Ogawa O, Akamatsu S

Front Oncol (2023);13:1139049

 

3. Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study.

Takata S, Morikawa K, Tanaka H, Itani H, Ishihara M, Horiuchi K, Kato Y, Ikemura S, Nakagawa H, Nakahara Y, Seki Y, Bessho A, Takahashi N, Hayashi K, Endo T, Takeyama K, Maekura T, Takigawa N, Kawase A, Endoh M, Nemoto K, Kishi K, Soejima K, Okuma Y, Yoshimura K, Saigusa D, Kanai Y, Ueda K, Togashi A, Matsutani N, Seki N

Ther Adv Med Oncol (2023);15:17588359231177021

 

4. Escherichia coli-derived outer-membrane vesicles induce immune activation and progression of cirrhosis in mice and humans.

Natsui K, Tsuchiya A, Imamiya R, Osada-Oka M, Ishii Y, Koseki Y, Takeda N, Tomiyoshi K, Yamazaki F, Yoshida Y, Ohashi R, Ling Y, Ueda K, Moritoki N, Sato K, Nakajima T, Hasegawa Y, Okuda S, Shibata S, Terai S

Liver Int (2023);43:1126-40

 

5. Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth.

Nagai K, Muto Y, Miura S, Takahashi K, Naruse Y, Hiruta R, Hashimoto Y, Uzuki M, Haga Y, Fujii R, Ueda K, Kawaguchi Y, Fujii M, Kitazume S

J Biol Chem (2023);299:105128

 

6. Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.

Miyagi T, Ueda K, Sugimoto M, Yagi T, Ito D, Yamazaki R, Narumi S, Hayamizu Y, Uji IH, Kuroda M, Kanekura K

iScience (2023);26:106957

 

7. Identification of Novel Senescent Markers in Small Extracellular Vesicles.

Misawa T, Hitomi K, Miyata K, Tanaka Y, Fujii R, Chiba M, Loo TM, Hanyu A, Kawasaki H, Kato H, Maezawa Y, Yokote K, Nakamura AJ, Ueda K, Yaegashi N, Takahashi A

Int J Mol Sci (2023);24

 

8. Protein profiling of extracellular vesicles from iPSC-derived astrocytes of patients with ALS/PDC in Kii peninsula.

Kobayashi H, Ueda K, Morimoto S, Ishikawa M, Leventoux N, Sasaki R, Hirokawa Y, Kokubo Y, Okano H

Neurol Sci (2023)

 

9. Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes.

Imamiya R, Shinohara A, Yakura D, Yamaguchi T, Ueda K, Oguro A, Minamiyama Y, Ichikawa H, Horiguchi Y, Osada-Oka M

mBio (2023):e0305122

 

10. Frontiers in mass spectrometry-based clinical proteomics for cancer diagnosis and treatment.

Haga Y, Minegishi Y, Ueda K

Cancer Sci (2023);114:1783-91

 

11. Identification of plexin D1 on circulating extracellular vesicles as a potential biomarker of polymyositis and dermatomyositis.

Uto K, Ueda K, Okano T, Akashi K, Takahashi S, Nakamachi Y, Imanishi T, Awano H, Morinobu A, Kawano S, Saegusa J

Rheumatology (Oxford) (2022);61:1669-79

 

12. Urinary extracellular vesicles signature for diagnosis of kidney disease.

Takizawa K, Ueda K, Sekiguchi M, Nakano E, Nishimura T, Kajiho Y, Kanda S, Miura K, Hattori M, Hashimoto J, Hamasaki Y, Hisano M, Omori T, Okamoto T, Kitayama H, Fujita N, Kuramochi H, Ichiki T, Oka A, Harita Y

iScience (2022);25:105416

 

13. Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure.

Takada S, Maekawa S, Furihata T, Kakutani N, Setoyama D, Ueda K, Nambu H, Hagiwara H, Handa H, Fumoto Y, Hata S, Masunaga T, Fukushima A, Yokota T, Kang D, Kinugawa S, Sabe H

Proc Natl Acad Sci U S A (2022)

 

14. Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer.

Saito Y, Matsuda S, Ohnishi N, Endo K, Ashitani S, Ohishi M, Ueno A, Tomita M, Ueda K, Soga T, Muthuswamy SK

Commun Biol (2022);5:403

 

15. Plasma exosomal DOK3 reflects immunological states in lung tumor and predicts prognosis of gefitinib treatment.

Ochiai R, Hayashi K, Yamamoto H, Fujii R, Saichi N, Shinchi H, Ishida T, Honda T, Shimizu T, Matsutani N, Seki N, Kawamura M, Ueda K

Cancer Sci (2022);113:3960-71

 

16. The Patterning and Proportion of Charged Residues in the Arginine-Rich Mixed-Charge Domain Determine the Membrane-Less Organelle Targeted by the Protein.

Miyagi T, Yamazaki R, Ueda K, Narumi S, Hayamizu Y, Uji IH, Kuroda M, Kanekura K

Int J Mol Sci (2022);23

 

17. Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations.

Minegishi Y, Kiyotani K, Nemoto K, Inoue Y, Haga Y, Fujii R, Saichi N, Nagayama S, Ueda K

Commun Biol (2022);5:831

 

18. Comprehensive Proteomic Profiling of Vitreous Humor in Ocular Sarcoidosis Compared with Other Vitreoretinal Diseases.

Komatsu H, Usui Y, Tsubota K, Fujii R, Yamaguchi T, Maruyama K, Wakita R, Asakage M, Shimizu H, Yamakawa N, Nezu N, Ueda K, Goto H

J Clin Med (2022);11

 

19. Elevated METTL9 is associated with peritoneal dissemination in human scirrhous gastric cancers.

Hara T, Tominaga Y, Ueda K, Mihara K, Yanagihara K, Takei Y

Biochem Biophys Rep (2022);30:101255

 

20. Fast and Ultrasensitive Glycoform Analysis by Supercritical Fluid Chromatography-Tandem Mass Spectrometry.

Haga Y, Yamada M, Fujii R, Saichi N, Yokokawa T, Hama T, Hayakawa Y, Ueda K

Anal Chem (2022);94:15948-55

 

21. Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques.

Haga Y, Ueda K

Glycoconj J (2022);39:303-13

 

22. CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis by proteomics of serum extracellular vesicles.

Futami Y, Takeda Y, Koba T, Narumi R, Nojima Y, Ito M, Nakayama M, Ishida M, Yoshimura H, Naito Y, Fukushima K, Takimoto T, Edahiro R, Matsuki T, Nojima S, Hirata H, Koyama S, Iwahori K, Nagatomo I, Shirai Y, Suga Y, Satoh S, Futami S, Miyake K, Shiroyama T, Inoue Y, Adachi J, Tomonaga T, Ueda K, Kumanogoh A

Int Immunol (2022)

 

23. Liquid Biopsy Targeting Monocarboxylate Transporter 1 on the Surface Membrane of Tumor-Derived Extracellular Vesicles from Synovial Sarcoma.

Yokoo S, Fujiwara T, Yoshida A, Uotani K, Morita T, Kiyono M, Hasei J, Nakata E, Kunisada T, Iwata S, Yonemoto T, Ueda K, Ozaki T

Cancers (Basel) (2021);13

 

24. Specimen-specific drift of densities defines distinct subclasses of extracellular vesicles from human whole saliva.

Yamamoto S, Okamura K, Fujii R, Kawano T, Ueda K, Yajima Y, Shiba K

PLoS One (2021);16:e0249526

 

25. Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression.

Sugiu K, Tazawa H, Hasei J, Yamakawa Y, Omori T, Komatsubara T, Mochizuki Y, Kondo H, Osaki S, Fujiwara T, Yoshida A, Kunisada T, Ueda K, Urata Y, Kagawa S, Ozaki T, Fujiwara T

Cancer Chemother Pharmacol (2021);88:513-24

 

26. Siblings with MAN1B1-CDG Showing Novel Biochemical Profiles.

Okamoto N, Ohto T, Enokizono T, Wada Y, Kohmoto T, Imoto I, Haga Y, Seino J, Suzuki T

Cells (2021);10

 

27. Azurocidin is loaded into small extracellular vesicles via its N-linked glycosylation and promotes intravasation of renal cell carcinoma cells.

Naito T, Jingushi K, Ueda K, Tsujikawa K

FEBS Lett (2021);595:2522-32

 

28. Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.

Miyata K, Imai Y, Hori S, Nishio M, Loo TM, Okada R, Yang L, Nakadai T, Maruyama R, Fujii R, Ueda K, Jiang L, Zheng H, Toyokuni S, Sakata T, Shirahige K, Kojima R, Nakayama M, Oshima M, Nagayama S, Seimiya H, Hirota T, Saya H, Hara E, Takahashi A

Proc Natl Acad Sci U S A (2021);118

 

29. G-quadruplex-forming nucleic acids interact with splicing factor 3B subunit 2 and suppress innate immune gene expression.

Matsumoto K, Okamoto K, Okabe S, Fujii R, Ueda K, Ohashi K, Seimiya H

Genes Cells (2021);26:65-82

 

30. Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres.

Koba T, Takeda Y, Narumi R, Shiromizu T, Nojima Y, Ito M, Kuroyama M, Futami Y, Takimoto T, Matsuki T, Edahiro R, Nojima S, Hayama Y, Fukushima K, Hirata H, Koyama S, Iwahori K, Nagatomo I, Suzuki M, Shirai Y, Murakami T, Nakanishi K, Nakatani T, Suga Y, Miyake K, Shiroyama T, Kida H, Sasaki T, Ueda K, Mizuguchi K, Adachi J, Tomonaga T, Kumanogoh A

ERJ Open Res (2021);7

 

31. Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis.

Imai S, Ooki T, Murata-Kamiya N, Komura D, Tahmina K, Wu W, Takahashi-Kanemitsu A, Knight CT, Kunita A, Suzuki N, Del Valle AA, Tsuboi M, Hata M, Hayakawa Y, Ohnishi N, Ueda K, Fukayama M, Ushiku T, Ishikawa S, Hatakeyama M

Cell Host Microbe (2021);29:941-58 e10

 

32. Colorectal Cancer-Derived CAT1-Positive Extracellular Vesicles Alter Nitric Oxide Metabolism in Endothelial Cells and Promote Angiogenesis.

Ikeda A, Nagayama S, Sumazaki M, Konishi M, Fujii R, Saichi N, Muraoka S, Saigusa D, Shimada H, Sakai Y, Ueda K

Mol Cancer Res (2021);19:834-46

 

33. Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine.

Chen C, Yamanaka Y, Ueda K, Li P, Miyagi T, Harada Y, Tezuka S, Narumi S, Sugimoto M, Kuroda M, Hayamizu Y, Kanekura K

J Cell Biol (2021);220

 

34. Exploration of the Proteomic Landscape of Small Extracellular Vesicles in Serum as Biomarkers for Early Detection of Colorectal Neoplasia.

Chang LC, Hsu YC, Chiu HM, Ueda K, Wu MS, Kao CH, Shen TL

Front Oncol (2021);11:732743

 

35. Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice.

Yamaguchi T, Higa K, Yagi-Yaguchi Y, Ueda K, Noma H, Shibata S, Nagai T, Tomida D, Yasu-Mimura R, Ibrahim O, Matoba R, Tsubota K, Hamrah P, Yamada J, Kanekura K, Shimazaki J

Sci Adv (2020);6:eaaz5195

 

36. Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism.

Wu AYT, Sung YC, Chen YJ, Chou STY, Guo V, Chien CY, Ko JJS, Yang AL, Huang HC, Chuang JC, Wu S, Ho MR, Ericsson M, Lin WW, Cheung CHY, Juan HF, Ueda K, Chen Y, Lai CPK

Adv Sci (2020);7:2001467

 

37. Mitochondria as a Platform for Dictating the Cell Fate of Cultured Human Corneal Endothelial Cells.

Numa K, Ueno M, Fujita T, Ueda K, Hiramoto N, Mukai A, Tokuda Y, Nakano M, Sotozono C, Kinoshita S, Hamuro J

Invest Ophthalmol Vis Sci (2020);61:10

 

38. Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells.

Hamuro J, Numa K, Fujita T, Toda M, Ueda K, Tokuda Y, Mukai A, Nakano M, Ueno M, Kinoshita S, Sotozono C

Invest Ophthalmol Vis Sci (2020);61:10

 

39. Polarized Expression of Ion Channels and Solute Carrier Family Transporters on Heterogeneous Cultured Human Corneal Endothelial Cells.

Hamuro J, Deguchi H, Fujita T, Ueda K, Tokuda Y, Hiramoto N, Numa K, Nakano M, Bush J, Ueno M, Sotozono C, Kinoshita S

Invest Ophthalmol Vis Sci (2020);61:47

 

40. Proteomic Analysis of Extracellular Vesicles for Cancer Diagnostics.

Wu AY, Ueda K, Lai CP

Proteomics (2019);19:e1800162

 

41. Prospective exosome-focused translational research for afatinib study of non-small cell lung cancer patients expressing EGFR (EXTRA study).

Okuma Y, Morikawa K, Tanaka H, Yokoyama T, Itani H, Horiuchi K, Nakagawa H, Takahashi N, Bessho A, Soejima K, Kishi K, Togashi A, Kanai Y, Ueda K, Horimoto K, Matsutani N, Seki N

Thorac Cancer (2019);10:395-400

 

42. INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.

Liu YY, Tanikawa C, Ueda K, Matsuda K

Int J Oncol (2019);54:1907-20

 

43. Leukocyteassociated immunoglobulinlike receptor 1 promotes tumorigenesis in RCC.

Jingushi K, Uemura M, Nakano K, Hayashi Y, Wang C, Ishizuya Y, Yamamoto Y, Hayashi T, Kinouchi T, Matsuzaki K, Kato T, Kawashima A, Ujike T, Nagahara A, Fujita K, Ueda K, Tsujikawa K, Nonomura N

Oncol Rep (2019);41:1293-303

 

44. Identification of Multisialylated LacdiNAc Structures as Highly Prostate Cancer Specific Glycan Signatures on PSA.

Haga Y, Uemura M, Baba S, Inamura K, Takeuchi K, Nonomura N, Ueda K

Anal Chem (2019);91:2247

 

45. Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.

Tanikawa C, Ueda K, Suzuki A, Iida A, Nakamura R, Atsuta N, Tohnai G, Sobue G, Saichi N, Momozawa Y, Kamatani Y, Kubo M, Yamamoto K, Nakamura Y, Matsuda K

Cell Rep (2018);22:1473-83

 

46. Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin.

Jingushi K, Uemura M, Ohnishi N, Nakata W, Fujita K, Naito T, Fujii R, Saichi N, Nonomura N, Tsujikawa K, Ueda K

Int J Cancer (2018);142:607-17

 

47. Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.

Deng B, Tarhan YE, Ueda K, Ren L, Katagiri T, Park JH, Nakamura Y

Neoplasia (2018);20:1038-44

 

48. Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.

Wang R, Deng X, Yoshioka Y, Vougiouklakis T, Park JH, Suzuki T, Dohmae N, Ueda K, Hamamoto R, Nakamura Y

Cancer Sci (2017);108:1203-9

 

49. Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.

Takahashi Y, Tanikawa C, Miyamoto T, Hirata M, Wang G, Ueda K, Komatsu T, Matsuda K

Int J Oncol (2017);51:724-36

 

50. EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.

Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K

Neoplasia (2017);19:185-95

 

51. Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53.

Miyamoto T, Lo PHY, Saichi N, Ueda K, Hirata M, Tanikawa C, Matsuda K

Sci Adv (2017);3:e1603204

 

52. MiR-21-5p in urinary extracellular vesicles is a novel biomarker of urothelial carcinoma.

Matsuzaki K, Fujita K, Jingushi K, Kawashima A, Ujike T, Nagahara A, Ueda Y, Tanigawa G, Yoshioka I, Ueda K, Hanayama R, Uemura M, Miyagawa Y, Tsujikawa K, Nonomura N

Oncotarget (2017);8:24668-78

 

53. p53-independent p21 induction by MELK inhibition.

Matsuda T, Kato T, Kiyotani K, Tarhan YE, Saloura V, Chung S, Ueda K, Nakamura Y, Park JH

Oncotarget (2017);8:57938-47

 

54. GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.

Lin J, Chung S, Ueda K, Matsuda K, Nakamura Y, Park JH

Neoplasia (2017);19:43-53

 

55. Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.

Tarhan YE, Kato T, Jang M, Haga Y, Ueda K, Nakamura Y, Park JH

Neoplasia (2016);18:265-72

 

56. Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.

Shimoda A, Ueda K, Nishiumi S, Murata-Kamiya N, Mukai SA, Sawada S, Azuma T, Hatakeyama M, Akiyoshi K

Sci Rep (2016);6:18346

 

57. Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma.

Sakha S, Muramatsu T, Ueda K, Inazawa J

Sci Rep (2016);6:38750

 

58. Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.

Nakakido M, Tamura K, Chung S, Ueda K, Fujii R, Kiyotani K, Nakamura Y

Int J Oncol (2016);49:868-76

 

59. A plasma diagnostic model of human T-cell leukemia virus-1 associated myelopathy.

Ishihara M, Araya N, Sato T, Saichi N, Fujii R, Yamano Y, Ueda K

Ann Clin Transl Neurol (2015);2:231-40

 

60. Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.

Ueda K, Ishikawa N, Tatsuguchi A, Saichi N, Fujii R, Nakagawa H

Sci Rep (2014);4:6232

 

61. Critical role of lysine 134 methylation on histone H2AX for gamma-H2AX production and DNA repair.

Sone K, Piao L, Nakakido M, Ueda K, Jenuwein T, Nakamura Y, Hamamoto R

Nat Commun (2014);5:5691

 

62. SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.

Hamamoto R, Toyokawa G, Nakakido M, Ueda K, Nakamura Y

Cancer Lett (2014);351:126-33

 

63. Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.

Fujitomo T, Daigo Y, Matsuda K, Ueda K, Nakamura Y

Int J Oncol (2014);45:147-56

 

64. Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).

Unoki M, Masuda A, Dohmae N, Arita K, Yoshimatsu M, Iwai Y, Fukui Y, Ueda K, Hamamoto R, Shirakawa M, Sasaki H, Nakamura Y

J Biol Chem (2013);288:6053-62

 

65. Plasma low-molecular-weight proteome profiling identified neuropeptide-Y as a prostate cancer biomarker polypeptide.

Ueda K, Tatsuguchi A, Saichi N, Toyama A, Tamura K, Furihata M, Takata R, Akamatsu S, Igarashi M, Nakayama M, Sato TA, Ogawa O, Fujioka T, Shuin T, Nakamura Y, Nakagawa H

J Proteome Res (2013);12:4497-506

 

66. Glycoproteomic strategies: From discovery to clinical application of cancer carbohydrate biomarkers.

Ueda K

Proteomics Clin Appl (2013);7:607-17

 

67. The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.

Kogure M, Takawa M, Saloura V, Sone K, Piao L, Ueda K, Ibrahim R, Tsunoda T, Sugiyama M, Atomi Y, Nakamura Y, Hamamoto R

Neoplasia (2013);15:1251-61

 

68. Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.

Ishihara M, Araya N, Sato T, Tatsuguchi A, Saichi N, Utsunomiya A, Nakamura Y, Nakagawa H, Yamano Y, Ueda K

Blood (2013);121:4340-7

 

69. Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring.

Toyama A, Nakagawa H, Matsuda K, Sato TA, Nakamura Y, Ueda K

Anal Chem (2012);84:9655-62

 

70. Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.

Tanikawa C, Espinosa M, Suzuki A, Masuda K, Yamamoto K, Tsuchiya E, Ueda K, Daigo Y, Nakamura Y, Matsuda K

Nat Commun (2012);3:676

 

71. Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.

Takawa M, Cho HS, Hayami S, Toyokawa G, Kogure M, Yamane Y, Iwai Y, Maejima K, Ueda K, Masuda A, Dohmae N, Field HI, Tsunoda T, Kobayashi T, Akasu T, Sugiyama M, Ohnuma S, Atomi Y, Ponder BA, Nakamura Y, Hamamoto R

Cancer Res (2012);72:3217-27

 

72. Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.

Nguyen MH, Ueda K, Nakamura Y, Daigo Y

Int J Oncol (2012);41:1285-96

 

73. Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.

Fujitomo T, Daigo Y, Matsuda K, Ueda K, Nakamura Y

Cancer Res (2012);72:4110-8

 

74. Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.

Chung S, Suzuki H, Miyamoto T, Takamatsu N, Tatsuguchi A, Ueda K, Kijima K, Nakamura Y, Matsuo Y

Oncotarget (2012);3:1629-40

 

75. A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma.

Ueda K, Saichi N, Takami S, Kang D, Toyama A, Daigo Y, Ishikawa N, Kohno N, Tamura K, Shuin T, Nakayama M, Sato TA, Nakamura Y, Nakagawa H

PLoS One (2011);6:e18567

 

76. Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer.

Toyama A, Nakagawa H, Matsuda K, Ishikawa N, Kohno N, Daigo Y, Sato TA, Nakamura Y, Ueda K

Proteome Sci (2011);9:18

 

77. C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.

Piao L, Nakagawa H, Ueda K, Chung S, Kashiwaya K, Eguchi H, Ohigashi H, Ishikawa O, Daigo Y, Matsuda K, Nakamura Y

Genes Chromosomes Cancer (2011);50:13-24

 

78. Development of serum glycoproteomic profiling technique; simultaneous identification of glycosylation sites and site-specific quantification of glycan structure changes.

Ueda K, Takami S, Saichi N, Daigo Y, Ishikawa N, Kohno N, Katsumata M, Yamane A, Ota M, Sato TA, Nakamura Y, Nakagawa H

Mol Cell Proteomics (2010);9:1819-28

 

79. Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.

Nguyen MH, Koinuma J, Ueda K, Ito T, Tsuchiya E, Nakamura Y, Daigo Y

Cancer Res (2010);70:5337-47

 

80. Involvement of C12orf32 overexpression in breast carcinogenesis.

Kim JW, Fukukawa C, Ueda K, Nishidate T, Katagiri T, Nakamura Y

Int J Oncol (2010);37:861-7

 

81. Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.

Kashiwaya K, Nakagawa H, Hosokawa M, Mochizuki Y, Ueda K, Piao L, Chung S, Hamamoto R, Eguchi H, Ohigashi H, Ishikawa O, Janke C, Shinomura Y, Nakamura Y

Cancer Res (2010);70:4024-33

 

82. Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.

Fukukawa C, Ueda K, Nishidate T, Katagiri T, Nakamura Y

Genes Chromosomes Cancer (2010);49:861-72

 

83. Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.

Ueda K, Fukase Y, Katagiri T, Ishikawa N, Irie S, Sato TA, Ito H, Nakayama H, Miyagi Y, Tsuchiya E, Kohno N, Shiwa M, Nakamura Y, Daigo Y

Proteomics (2009);9:2182-92

 

84. Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.

Tanikawa C, Ueda K, Nakagawa H, Yoshida N, Nakamura Y, Matsuda K

Cancer Res (2009);69:8761-9

 

85. Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.

Ajiro M, Katagiri T, Ueda K, Nakagawa H, Fukukawa C, Lin ML, Park JH, Nishidate T, Daigo Y, Nakamura Y

Int J Oncol (2009);35:673-81

 

86. Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.

Ueda K, Katagiri T, Shimada T, Irie S, Sato TA, Nakamura Y, Daigo Y

J Proteome Res (2007);6:3475-83

 

87. Proteomic identification of Bcl2-associated athanogene 2 as a novel MAPK-activated protein kinase 2 substrate.

Ueda K, Kosako H, Fukui Y, Hattori S

J Biol Chem (2004);279:41815-21

 

88. Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.

Ueda K, Arakawa H, Nakamura Y

Oncogene (2003);22:5586-91